The coexistence of obstructive sleep apnea (OSA) and chronic obstructive pulmonary
disease (COPD) has been described as the “overlap syndrome” (OS) [
[1]
]. Compared to patients with simple OSA, patients with OS exhibit a lower nocturnal
oxygen saturation (SaO2), more profound desaturations during the apneic events and often severe hypoventilation
particularly during rapid-eye-movements sleep [
[2]
].Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to European Journal of Internal MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- COPD-OSA overlap syndrome: evolving evidence regarding epidemiology, clinical consequences, and management.Chest. 2017 Dec; 152: 1318-1326
- Association of chronic obstructive pulmonary disease and sleep apnea syndrome.Am J Respir Crit Care Med. 1995 Jan; 151: 82-86
- Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome.Circulation. 2005; 112: 2660-2665
- Effect of treatment with nasal continuous positive airway pressure on ventilatory response to hypoxia and hypercapnia in patients with sleep apnea syndrome.Chest. 2006; 130: 774-779
- International classification of sleep disorders.3rd ed. American Academy of Sleep Medicine, Darien, IL2014
- Global initiative for chronic obstructive lung disease: The global strategy for the diagnosis, management and prevention of COPD.http://www.goldcopd.org/Date: 2017
- Comorbid obstructive sleep apnoea and chronic obstructive pulmonary disease and the risk of cardiovascular disease.J Thorac Dis. 2018; 10: S4253-S4261
- Evaluation of right ventricular remodeling using cardiacmagnetic resonance imaging in co-existent chronic obstructive pulmonary disease and obstructive sleep apnea.COPD. 2013; 10: 4-10
- Prevalence of comorbidities in patients with obstructive sleep apnea syndrome, overlap syndrome and obesity hypoventilation syndrome.Clin Respir J. 2018 May; 12: 1905-1911
- Comorbidities and survival in obstructive sleep apnoea beyond the age of 50.Eur J Clin Invest. 2013; 43: 27-33
Article info
Publication history
Published online: September 05, 2019
Accepted:
August 21,
2019
Received:
August 16,
2019
Identification
Copyright
© 2019 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
