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Frailty and subsequent mortality in the elderly: A risk assessment

Published:October 09, 2019DOI:https://doi.org/10.1016/j.ejim.2019.09.010
      I read with great interest the paper by Zucchelli et al. [
      • Zucchelli A
      • Vetrano DL
      • Marengoni A
      • Grande G
      • Romanelli G
      • Calderón-Larrañaga A
      • et al.
      Frailty predicts short-term survival even in older adults without multimorbidity.
      ], which is a cohort study to determine the effect of frailty on mortality in adults aged 60+ without multi-morbidity. Within the first 5 years of follow-up, adjusted hazard ratios (HRs) (95% confidence intervals [CIs]) of pre-frail and frail participants for mortality were 2.08 (1.15–3.76) and 2.69 (1.22–5.97), respectively. In contrast, the significance disappeared beyond 5 years, and frailty and pre-frailty were closely related to relatively short-term mortality in older adults free from multi-morbidity. I have some queries on their study.

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