Left ventricular (LV) thrombus is a known complication of acute myocardial infarction
(AMI), with a reported incidence ranging from 0.7 to 4.3% in the era of primary percutaneous
coronary intervention (PCI) [
[1]
,
[2]
]. Previous studies have demonstrated that anterior ST segment elevation myocardial
infarction (STEMI) and a left ventricular ejection fraction (LVEF) ≤ 40% are significant
predictors of LV thrombus development [
[3]
]. On the other hand, non-STEMI (NSTEMI) represents a distinct pathophysiology and
NSTEMI patients often undergo early, as opposed to immediate revascularisation as
in STEMI patients [
[4]
]. With the majority of reported clinical series on LV thrombus solely focused on post-STEMI
patients [
[5]
], it is unknown whether NSTEMI patients with LV thrombus have significant differences
in terms of clinical characteristics and outcomes. Hence, we aimed to characterise
post-AMI patients with concomitant LV thrombus formation and examine the impact of
NSTEMI and LVEF on various outcomes in these patients.To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to European Journal of Internal MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction.J Thromb Thrombolysis. 2016; 41: 365-373
- Clinical characteristics and risk factors of left ventricular thrombus after acute myocardial infarction: a matched case-control study.Chin Med J. 2015; 128: 2415
- Frequency of left ventricular thrombus in patients with anterior wall acute myocardial infarction treated with percutaneous coronary intervention and dual antiplatelet therapy.Am J Cardiol. 2010; 106: 1197-1200
- Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI.Am J Med. 2011; 124: 40-47
- Left ventricular thrombi after STEMI in the primary PCI era: a systematic review and meta-analysis.Int J Cardiol. 2016; 221: 554-559
- Left ventricular thrombus incidence and behavior studied by serial two-dimensional echocardiography in acute anterior myocardial infarction: left ventricular wall motion, systemic embolism and oral anticoagulation.J Am Coll Cardiol. 1989; 13: 1514-1520
- Left ventricular thrombus formation after acute myocardial infarction.Heart. 2012; 98: 1743-1749
- Myocardial 'stunning' in man.Circulation. 1992; 86: 1671-1691
- The prognostic effect of left ventricular thrombus formation after acute myocardial infarction in the contemporary era of primary percutaneous coronary intervention: a meta-analysis.Eur J Intern Med. 2019; (. In press)https://doi.org/10.1016/j.ejim.2019.10.029
- Prediction of mortality after primary percutaneous coronary intervention for acute myocardial infarction: the Cadillac risk score.J Am Coll Cardiol. 2005; 45: 1397-1405
Article info
Publication history
Published online: January 16, 2020
Accepted:
January 8,
2020
Received:
November 24,
2019
Identification
Copyright
© 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
