Cardiovascular (CV) risk associated with Systemic Erythematosus Lupus (SLE) yet remains an issue of great interest and current debate. Results from a large number of epidemiological studies clearly indicate SLE as a clinical condition associated with an increased CV risk. Such risk is estimated to be as more than twofold higher than what predicted by traditional CV risk factors (CVRFs) such as age, sex, hypertension, diabetes mellitus, dyslipidemia, smoking, sedentary behavior and obesity [
- Tektonidou MG
- Wang Z
- Ward MM
Brief report: trends in hospitalizations due to acute coronary syndromes and stroke in patients with systemic lupus erythematosus, 1996 to 2012.
Arthritis Rheumatol. 2016; 68: 2680-2685
- Arkema EV
- Svenungsson E
- Von Euler M
- Sjöwall C
- Simard JF
Stroke in systemic lupus erythematosus: a Swedish population-based cohort study.
Ann Rheum Dis. 2017; 76: 1544-1549
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to European Journal of Internal Medicine
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Brief report: trends in hospitalizations due to acute coronary syndromes and stroke in patients with systemic lupus erythematosus, 1996 to 2012.Arthritis Rheumatol. 2016; 68: 2680-2685
- Stroke in systemic lupus erythematosus: a Swedish population-based cohort study.Ann Rheum Dis. 2017; 76: 1544-1549
- Risk factors in cardiovascular disease in systemic lupus erythematosus.Curr Cardiol Rev. 2013; 9: 15-19
- Impact of antimalarial (AM) on serum lipids in systemic lupus erythematosus (SLE) patients: a systematic review and meta-analysis.Medicine (Baltimore). 2019; 98: e15030
- 2019 update of the EULAR recommendations for the management of systemic lupus erythematosus.Ann Rheum Dis. 2019; 78: 736-745
- The epidemiology of atherosclerotic cardiovascular disease among patients with SLE: a systematic review.Semin Arthritis Rheum. 2013; 43: 77-95
- Risk of myocardial infarction and stroke in newly diagnosed systemic lupus erythematosus: a general population-based study.Arthritis Care Res (Hoboken). 2017; 69: 849-856
- Disease trends over time and CD4+CCR5+ T-cells expansion predict carotid atherosclerosis development in patients with systemic lupus erythematosus.Nutr Metab Cardiovasc Dis. 2018; 28: 53-63
Salvetti M, Painia A, Andreolia L, Stassaldia D, Aggiustia C, Bertacchinia F, Agabiti Rosei C, Piantonia S, Franceschini F, Tincania A, Muiesan ML. Cardiovascular target organ damage in premenopausal systemic lupus erythematosus patients and in controls: Are there any differences? Eur J Intern Med (in press) - https://doi.org/10.1016/j.ejim.2019.12.001.
Published online: January 27, 2020
Accepted: January 20, 2020
Received: January 7, 2020
© 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
ScienceDirectAccess this article on ScienceDirect
- Cardiovascular target organ damage in premenopausal systemic lupus erythematosus patients and in controls: Are there any differences?European Journal of Internal MedicineVol. 73
- PreviewSince 1976 the bimodal pattern of mortality in patients with Systemic Lupus Erythematosus (SLE) was described: the first peak (3 years after diagnosis) due to active disease and the later peak (4–20 years after diagnosis) due to cardiovascular (CV) disease . Patients with SLE are at least 2- to 3-fold elevated risks of myocardial infarction, congestive heart failure and cerebrovascular disease compared to the general population ; CV diseases represent one of the most important causes of death in these patients .