Giant cell arteritis (GCA) is classified as a large vessel vasculitis according to
the Chapel Hill nomenclature [
[1]
]. GCA is present worldwide but the reported incidence rates are highly variable depending
on the location. The incidence is high in the North of Europe, especially in Norway
(32.8/100,000 older than 50) or in North America (19.8/100,000 older than 50) [
2
,
3
] whereas the disease seems to be rare in North Africa [
[4]
] or in Japan (1.7/100,000 older than 50) [
[5]
]. Data from other areas are scarce. In the South hemisphere, studies performed in
Oceania showed that the incidence varies from 3.2 to 12.7/100,000 individuals older
than 50, respectively in Australia and New Zealand [
6
,
7
]. This suggests specific risk factors, related to the environment or genetic predisposition.
In order to improve the knowledge about GCA epidemiology, we conducted a study in
La Reunion island, a territory characterized by a marked genetic admixture and its
location in Indian Ocean where no data are available. The main ethnics groups in La
Reunion island are from Africa, Madagascar, India and Europe with a recent census
estimate of 850,000 inhabitants.Keywords
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Article info
Publication history
Published online: January 31, 2020
Accepted:
January 26,
2020
Received in revised form:
January 4,
2020
Received:
August 3,
2019
Identification
Copyright
© 2020 Published by Elsevier B.V. on behalf of European Federation of Internal Medicine.