Metabolic Syndrome (MS) is a cluster of elevated Blood Pressure (BP) and glucose,
lipids alterations (elevated triglycerides or low HDL-cholesterol) and abdominal obesity
that has been associated with a significant increase in Cardio-Vascular (CV) events
and mortality [
[1]
]. It is highly prevalent in hypertensive patients [
- Khang Y.H.
- Cho S.I.
- Kim H.R.
Risks for cardiovascular disease, stroke, ischaemic heart disease, and diabetes mellitus
associated with the metabolic syndrome using the new harmonised definition: findings
from nationally representative longitudinal data from an asian population.
Atherosclerosis. 2010; 213: 579-585
[2]
] but data on the longitudinal trends of BP values in hypertensives with and without
MS are very limited [
- Barrios V.
- Escobar C.
- Calderón A.
- Llisterri J.L.
- Alegría E.
- Muñiz J.
- Matalí A
Prevalence of the metabolic syndrome in patients with hypertension treated in general
practice in spain: an assessment of blood pressure and low-density lipoprotein cholesterol
control and accuracy of diagnosis.
J Cardiometab Syndr. 2007; 2: 9-15
[3]
,
[4]
]. Furthermore, MS is characterized by an increase in Pulse Wave Velocity (PWV) but
this relationship has been poorly evaluated in longitudinal studies.Keywords
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to European Journal of Internal MedicineAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Risks for cardiovascular disease, stroke, ischaemic heart disease, and diabetes mellitus associated with the metabolic syndrome using the new harmonised definition: findings from nationally representative longitudinal data from an asian population.Atherosclerosis. 2010; 213: 579-585
- Prevalence of the metabolic syndrome in patients with hypertension treated in general practice in spain: an assessment of blood pressure and low-density lipoprotein cholesterol control and accuracy of diagnosis.J Cardiometab Syndr. 2007; 2: 9-15
- Mean and yearly changes in blood pressure with age in the metabolic syndrome: the desir study.Hypertens Res. 2011; 34: 91-97
- Associations of metabolic disorder factors with the risk of uncontrolled hypertension: a follow-up cohort in rural china.Sci Rep. 2017; 7: 743
- Metabolic syndrome and age-related progression of aortic stiffness.J Am Coll Cardiol. 2006; 47: 72-75
- The effects of changes in the metabolic syndrome detection status on arterial stiffening: a prospective study.Hypertens Res. 2006; 29: 673-678
- Determinants of carotid-femoral pulse wave velocity progression in hypertensive patients over a 3.7 years follow-up.Blood Press. 2018; 27: 32-40
- Carotid and aortic stiffness in essential hypertension and their relation with target organ damage: the catod study.J Hypertens. 2017; 35: 310-318
- The reference values for arterial stiffness’ collaboration. determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values.Eur. Heart J. 2010; 31: 2338-2350
- Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension.Circulation. 1995; 92: 2911-2918
- Selective angiotensin receptor antagonisms with valsartan decreases arterial stiffness independently of blood pressure lowering in hypertensive patients.Hypertens Res. 2005; 28: 937-943
- Classes of antihypertensive medications and blood pressure control in relation to metabolic risk factors.Hypertens. 2012; 30: 188-193
Article info
Publication history
Published online: February 18, 2020
Accepted:
February 11,
2020
Received in revised form:
February 4,
2020
Received:
December 19,
2019
Identification
Copyright
© 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
