The article of Alexandre, Leo et al. [
[1]
] about the correlation of Iron Deficiency without Anemia (IDWA) with intestinal cancer
was an interesting read. Essentially Iron Deficiency (ID) appears as a potential biomarker
indicating or even mediating morphological alterations. However the findings of the
study were not enough to establish a correlation of ID with a dire need of invasive
investigation (endoscopy). We have encountered a similar pattern of ID implication
in a study we are currently conducting. The purpose of this letter is to discuss ID
in this context focusing on the benefit of testing ID and the need for less invasive
approaches.- Leo Alexandre
- Charelle Manning
- Simon Chan
Prevalence of gastrointestinal malignancy in iron deficiency without anaemia: a systematic
review and meta-analysis.
Eur J Int Med. 2019; https://doi.org/10.1016/j.ejim.2019.12.015
Keywords
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References
- Prevalence of gastrointestinal malignancy in iron deficiency without anaemia: a systematic review and meta-analysis.Eur J Int Med. 2019; https://doi.org/10.1016/j.ejim.2019.12.015
- Effect of iron supplementation on mental and motor development in children: systematic review of randomised controlled trials.Pub Health Nutr. 2005; 8: 117-132
- Effect of iron supplementation on physical growth in children: systematic review of randomised controlled trials.Pub Health Nutr. 2006; 9: 904-920
- Effects of daily iron supplementation in primary-school-aged children: systematic review and meta-analysis of randomized controlled trials.CMAJ. 2013; 19: 791-802
- A review of studies on the effect of iron deficiency on cognitive development in children.J Nutr. 2001; 131: 649-668
- Colorectal cancer and markers of anemia.Eur J Cancer Prev. 2018; 27: 530-538
- The potential of quantum computing and machine learning to advance clinical research and change the practice of medicine.Mo Med. 2018; 115: 463-467
Article info
Publication history
Published online: March 23, 2020
Accepted:
March 10,
2020
Received:
February 16,
2020
Identification
Copyright
© 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
