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Iron deficiency in pregnancy and gastrointestinal cancer: addressing a common gap

Published:March 23, 2020DOI:https://doi.org/10.1016/j.ejim.2020.03.012
      The article of Alexandre, Leo et al. [
      • Leo Alexandre
      • Charelle Manning
      • Simon Chan
      Prevalence of gastrointestinal malignancy in iron deficiency without anaemia: a systematic review and meta-analysis.
      ] about the correlation of Iron Deficiency without Anemia (IDWA) with intestinal cancer was an interesting read. Essentially Iron Deficiency (ID) appears as a potential biomarker indicating or even mediating morphological alterations. However the findings of the study were not enough to establish a correlation of ID with a dire need of invasive investigation (endoscopy). We have encountered a similar pattern of ID implication in a study we are currently conducting. The purpose of this letter is to discuss ID in this context focusing on the benefit of testing ID and the need for less invasive approaches.

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