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Alcohol intake and atrial fibrillation: A new topic in gender medicine

Published:April 20, 2020DOI:https://doi.org/10.1016/j.ejim.2020.04.034
      Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in clinical practice and a major risk factor for stroke, heart failure, hospitalization and mortality [
      • Patel N.J.
      • et al.
      Contemporary trends of hospitalization for atrial fibrillation in the United States, 2000 through 2010: implications for healthcare planning.
      ,
      • Lip G.Y.H.
      • Brechin C.M.
      • Lane D.A.
      The global burden of atrial fibrillation and stroke: a systematic review of the epidemiology of atrial fibrillation in regions outside North America and Europe.
      ,
      • Angeli F.
      • et al.
      Atrial fibrillation and mortality in patients with acute myocardial infarction: a systematic overview and meta-analysis.
      ]. It affects approximately 1–2% of the general population and its incidence doubles with each decade after 50 years [
      • Patel N.J.
      • et al.
      Contemporary trends of hospitalization for atrial fibrillation in the United States, 2000 through 2010: implications for healthcare planning.
      ,
      • Zoni-Berisso M.
      • et al.
      Frequency, patient characteristics, treatment strategies, and resource usage of atrial fibrillation (from the Italian Survey of Atrial Fibrillation Management [ISAF] study).
      ]. Numerous underlying risk factors for AF are well established. They include age, sex, hypertension, coronary artery disease, heart failure, diabetes, chronic pulmonary disease, and obesity [
      • Patel N.J.
      • et al.
      Contemporary trends of hospitalization for atrial fibrillation in the United States, 2000 through 2010: implications for healthcare planning.
      ,
      • Angeli F.
      • et al.
      Detrimental impact of chronic obstructive pulmonary disease in atrial fibrillation: new insights from umbria atrial fibrillation registry.
      ,
      • Verdecchia P.
      • Angeli F.
      • Reboldi G.
      Hypertension and atrial fibrillation: doubts and certainties from basic and clinical studies.
      ]. Nonetheless, various new or emerging risk factors have the potential to improve global risk assessment for AF. Among these, alcohol consumption has been the object of several investigations.

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