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The additive diagnostic value of heart-type fatty acid binding protein in patients presenting early with chest pain

      Acute myocardial infarction (AMI) is one of the most serious conditions encountered in the emergency room (ER), with outcomes that are highly affected by the time elapsed since symptoms onset. The diagnosis of AMI is currently based on clinical judgment, electrocardiogram (ECG), biomarkers, and in cases of uncertainty, imaging modalities. Currently, high-sensitivity troponin (hs-cTnI) is the recommended biomarker for early diagnosis of AMI [
      • Thygesen K
      • Alpert JS
      • Jaffe AS
      • Chaitman BR
      • Bax JJ
      • Morrow DA
      • et al.
      Fourth universal definition of myocardial infarction (2018).
      ]. Among other putative biomarkers, heart-type fatty acid binding protein (H-FABP) has recently gained focus as a diagnostic and prognostic biomarker [
      • Xu LQ
      • Yang YM
      • Tong H
      • Xu CF
      Early diagnostic performance of heart-type fatty acid binding protein in suspected acute myocardial infarction: evidence from a meta-analysis of contemporary studies.
      ].
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