After the pivotal phase 3 trials on venous thromboembolism (VTE) treatment with non-vitamin
K antagonist oral anticoagulants (NOACs) had been performed some 10 years ago, these
drugs have now become the standard anticoagulant treatment of VTE. While randomized
controlled trials (RCT) carefully select patients to allow homogeneous comparisons
between the randomized groups, real world evidence (RWE) is required from a much larger
patient population with a high variation of clinical characteristics. Therefore, it
is crucial to ensure that the efficacy and safety observed in phase 3 trials can be
confirmed in everydays clinical settings.
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Biography
Dr. Bauersachs reports personal fees from Bristol Myers Squibb, personal fees from Bayer AG, personal fees from Daichii-Sankyo, personal fees from Leo Pharma, all outside the submitted work.
Article info
Publication history
Published online: October 07, 2020
Accepted:
October 5,
2020
Received:
September 29,
2020
Identification
Copyright
© 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
