Highlights
- •Adjusted incidence of hospitalizations for PE was higher in COPD patients.
- •In hospital mortality (IHM) was significantly associated with suffering COPD.
- •IHM predictors included age, comorbidity, atrial fibrillation and oxygen dependence
- •Obesity was associated with lower IHM in COPD patients hospitalized with PE.
Abstract
Background
To examine the incidence, clinical characteristics, and in-hospital outcomes of pulmonary
embolism (PE) among hospitalized patients with or without chronic obstructive pulmonary
disease (COPD) in Spain, and to identify predictors of in-hospital-mortality (IHM)
after PE among patients with and without COPD.
Methods
We included all patients aged ≥ 40 years who were hospitalised for PE between 2016
and 2018. Data were collected from the Spanish National Hospital Discharge Database.
Results
We identified 47,190 hospitalizations for PE during the study period, 7.49% with COPD.
Adjusted incidence of PE was higher in COPD patients than in those without COPD (IRR
1.16; 95%CI 1.13-1.19). Crude IHM was significantly higher in PE hospitalized patients
with COPD than in those without COPD (9.86% vs 3.59%; p<0.001). Predictor factors
of IHM in COPD patients with PE included older age, higher Charlson comorbidity index,
atrial fibrillation, massive PE and dependence on oxygen prior to hospital admission.
However, obesity was associated with lower IHM. For PE hospitalized patients, suffering
COPD increased the probability of dying in the hospital (adjusted OR 2.84; 95%CI 2.27-3.55).
Conclusions
Our results revealed that incidence of PE was higher in COPD patients than in those
without COPD. Furthermore, COPD was a risk factor for IHM after PE.
Keywords
Abbreviations:
BMI (body mass index), CCI (Charlson comorbidity index), CI (confidence intervals), COPD (chronic obstructive pulmonary disease), DRG (diagnosis-related groups), ICD-10 (international classification of diseases-10th revision), IHM (in-hospital-mortality), IRR (incidence rate ratios), LOHS (length of hospital stay), OR (odds ratio), PE (pulmonary embolism), PSM (propensity score matching), SNHDD (Spanish national hospital discharge database)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: November 26, 2020
Accepted:
November 11,
2020
Received in revised form:
November 4,
2020
Received:
October 26,
2020
Identification
Copyright
© 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
