Adropin acts as an energy regulator through lipid and glucose metabolism [
[1]
,
[2]
]. This 76 amino acid protein encoded by the ENHO (Energy Homeostasis Associated Gene)
gene is primarily expressed in the liver and the central nervous system. Therefore,
adropin was also detected in muscle, heart, pancreas, and kidneys [
[1]
,
[2]
]. Adropin is associated with carbohydrate-lipid metabolism, metabolic diseases [
2
,
3
,
4
,
5
], endothelial function [
[6]
] and cardiovascular disease [
3
,
4
,
5
,
6
,
7
]. Additionally, Aydin et al. reported that adropin is produced locally in the glomerulus,
peritubular interstitial cells, and peritubular capillary endothelial cells of the
rat kidneys [
- Jasaszwili M.
- Billert M.
- Strowski M.Z.
- Nowak K.W.
- Skrzypski M.
Adropin as a fat-burning hormone with multiple functions-review of a decade of research.
Molecules. 2020 Jan 27; 25 (PMID:32012786; PMCID: PMC7036858): 549https://doi.org/10.3390/molecules25030549
[4]
].Keywords
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References
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- Elevated adropin: a candidate diagnostic marker for myocardial infarction in conjunction with troponin-I.Peptides. 2014; 58: 91-97
- Adropin: a key component and potential gatekeeper of metabolic disturbances in policystic ovarian syndrome.Clin Exp Obstet Gynecol. 2014; 41: 310-312
- Correlation of serum adropin level with coronary artery disease.Chen J Zhonghua Yi Xue Za Zhi. 2014; 94: 1255-1257
- Adropin as a fat-burning hormone with multiple functions-review of a decade of research.Molecules. 2020 Jan 27; 25 (PMID:32012786; PMCID: PMC7036858): 549https://doi.org/10.3390/molecules25030549
- Adropin and irisin in arterial hypertension, diabetes mellitus and chronic kidney disease.Adv Clin Exp Med. 2019; 28: 1571-1575https://doi.org/10.17219/acem/104551
- Adropin and irisin: new biomarkers of cardiac status in patients with end-stage renal disease? A preliminary study.Adv Clin Exp Med. 2019; 28: 347-353https://doi.org/10.17219/acem/81538
- Serum neutrophil gelatinase-associated lipocalin correlates with kidney function in renal allograft recipients.Clin Transplant. 2009; : 681-686
Article info
Publication history
Published online: December 16, 2020
Accepted:
November 11,
2020
Received:
November 2,
2020
Identification
Copyright
© 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
