Highlights
- •A higher CHA2DS2-VASc score is correlated to higher cytokine levels
- •The CHA2DS2-VASc score is an expression of a complex clinical status
- •The CHA2DS2-VASc score is inversely associated with SPPB, an index of frailty
- •An association also exists between IL-6 levels and frailty
- •In AF, inflammation could mediate the link between CHA2DS2-VASc score and frailty
Keywords
Abbreviations:
AF (atrial fibrillation), GDS (Geriatric Depression Scale), ECV (electrical cardioversion), IL-6 (interleukin-6), MMSE (Mini-Mental State Examination), OPG (osteoprotegerin), SPPB (Short Physical Performance Battery)To read this article in full you will need to make a payment
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References
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Article info
Publication history
Published online: December 16, 2020
Accepted:
December 4,
2020
Received in revised form:
November 19,
2020
Received:
October 18,
2020
Footnotes
☆The other participants to the PURE-Rhythm Trial are: Paolo Pieragnoli, MD, PhD; Giuseppe Ricciardi, MD, PhD (Electrophysiology Laboratory, University of Florence and AOU Careggi, Florence, Italy); Giulia Pelagalli, MD; Riccardo Franci Montorzi, MD; Francesca Tarantini, MD, PhD (Geriatric Intensive Care Unit and Geriatric Arrhythmia Unit, University of Florence and AOU Careggi, Florence, Italy)
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Copyright
© 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
