immune thrombocytopenic purpura (ITP) is a rare hematologic disorder characterized
by isolated thrombocytopenia due to platelet destruction, without abnormalities of
erythrocyte or leukocyte number or morphology. The incidence ranges between 1.6 to
3.9 per 100.000 patient-years, with higher rates among the elderly [
[1]
].- Neunert C
- Terrell DR
- Arnold DM
- et al.
American Society of Hematology 2019 guidelines for immune thrombocytopenia.
Blood Adv. 2019; 3 ([published correction appears in Blood Adv. 2020 Jan 28;4(2):252]): 3829-3866https://doi.org/10.1182/bloodadvances.2019000966
Keywords
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References
- American Society of Hematology 2019 guidelines for immune thrombocytopenia.Blood Adv. 2019; 3 ([published correction appears in Blood Adv. 2020 Jan 28;4(2):252]): 3829-3866https://doi.org/10.1182/bloodadvances.2019000966
- Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review.J ThrombHaemost. Mar 2015; 13 (Epub 2015 Jan 14. PMID: 25495497; PMCID: PMC4991942): 457-464https://doi.org/10.1111/jth.12813
- Increased procoagulant cell-derived microparticles (C-MP) in splenectomized patients with ITP.Thromb Res. 2008; 122: 599-603
- on behalf the subcommittee on control of anti- coagulation on the Scientific and Standardization committee of the International Society on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations and antihemostatic medicinal products in non-surgical patients.J ThrombHaemost. 2005; 3: 692-694
- Splenectomy is associated with a higher risk for venous thromboembolism: A prospective cohort study.Int J Surg. 2015; 24: 27-32https://doi.org/10.1016/j.ijsu.2015.10.011
- Thrombopoietin Receptor Agonists: Ten Years Later.Haematologica. June 2019; 104: 1112-1123
Leader A, Ten Cate V, Ten Cate-Hoek AJ, Beckers EAM, Spectre G, Giaccherini C, Gurevich-Shapiro A, Krashin E, Raanani P, Schouten HC, Falanga A, Ten Cate H. Anticoagulation in thrombocytopenic patients with hematological malignancy: A multinational clinical vignette-based experiment. Eur J Intern Med. 2020 Jul;77:86-96. doi: 10.1016/j.ejim.2020.03.005. Epub 2020 Mar 13. PMID: 32173172.
Article info
Publication history
Published online: February 07, 2021
Accepted:
January 24,
2021
Received in revised form:
January 21,
2021
Received:
January 14,
2021
Identification
Copyright
© 2021 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
