Cardiovascular disease (CVD) accounts for up to 35% of mortality in patients with
systemic lupus erythematosus (SLE) [
[1]
]. Emerging evidence supports that SLE disease activity is associated with up to two
times higher cardiovascular (CV) risk than traditional risk factors [
[2]
]. According to an interesting recent study of Salvetti et al. left ventricular function
in premenopausal women suffering from SLE was inferior compared to control subjects
matched for sex, age, body mass index (BMI), blood pressure and antihypertensive therapy.
Moreover, the femoral and carotid pulse wave velocity were affected by the treatment
of SLE with steroids [
[3]
]. These findings suggest that younger SLE patients are not spared from cardiovascular
disease [
[1]
]. Hence, identifying further risk factors associated with CV events in SLE is essential,
in order to improve CV care and decrease CV morbidity and mortality among these patients.To read this article in full you will need to make a payment
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References
Deane K. Cardiovascular Disease a Leading Cause of Death in Lupus. Medscape.
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- Systemic lupus erythematosus in a multiethnic US cohort (LUMINA). XXIII. Baseline predictors of vascular events.Arthritis Rheum. 2004; 50: 3947-3957https://doi.org/10.1002/art.20622
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Article info
Publication history
Published online: February 17, 2021
Accepted:
February 8,
2021
Received in revised form:
February 5,
2021
Received:
January 16,
2021
Footnotes
Paraphrasing the popular latin proverb “homo homini lupus (a man is a wolf to another man)”. “Cor (heart in latin) homini lupus” refers to the cardiovascular implications of SLE indicating that cardiovascular disease adds up to SLE morbidity and mortality
Identification
Copyright
© 2021 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
