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Atrial high rate episodes as a marker of atrial cardiomyopathy: In the quest of the Holy Grail. Author's reply

  • Marco Vitolo
    Affiliations
    Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy

    Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy

    Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom
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  • Jacopo F. Imberti
    Affiliations
    Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy

    Clinical and Experimental Medicine PhD Program, University of Modena and Reggio Emilia, Modena, Italy

    Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom
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  • Marco Proietti
    Affiliations
    Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom

    Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

    Geriatric Unit, IRCCS Istituti Clinici Scientifici Maugeri, Milan, Italy
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  • Gregory Y.H. Lip
    Affiliations
    Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom

    Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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  • Giuseppe Boriani
    Correspondence
    Corresponding author.
    Affiliations
    Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, Modena, Italy
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Published:January 21, 2022DOI:https://doi.org/10.1016/j.ejim.2022.01.032
      We appreciate Doundoulakis and colleagues for the interest in our article [
      • Vitolo M.
      • Imberti J.F.
      • Maisano A.
      • Albini A.
      • Bonini N.
      • Valenti A.C.
      • et al.
      Device-detected atrial high rate episodes and the risk of stroke/thrombo-embolism and atrial fibrillation incidence: a systematic review and meta-analysis.
      ,
      • Doundoulakis I.
      • Tsiachris D.
      • Gatzoulis K.A.
      • Stefanadis C.
      • Tsioufis K.
      Atrial high rate episodes as a marker of atrial cardiomyopathy: in the quest of the Holy Grail.
      ]. We take advantage of the opportunity to reply focusing on some aspects that we believe are clinically important. In the last decade the interest surrounding atrial high rate episodes (AHRE) markedly increased [
      • Boriani G.
      • Vitolo M.
      • Imberti J.F.
      • Potpara T.S.
      • Lip G.Y.H.
      What do we do about atrial high rate episodes?.
      ]. AHREs are a relatively new clinical concept and their optimal management, especially regarding the use of oral anticoagulants (OACs), is still matter of debate [
      • Boriani G.
      • Vitolo M.
      • Imberti J.F.
      • Potpara T.S.
      • Lip G.Y.H.
      What do we do about atrial high rate episodes?.
      ].
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