With the continuous development of cancer treatment, patients with cancer have dramatically
improved, with several cancer populations experiencing a median survival well beyond
5 years.
[1]
However, malignancy cancer has an innegligible impact on the cardiovascular system,
not only the cancer itself, but also the adverse effects of treatments (drugs or radiation).
Recently, increasing data have shown that cancer survivors have increased rates of
major cardiovascular events, including cardiac arrest, with poorer outcomes.
[2]
However, it remains controversial whether the malignant cancer is a risk factor of
in-hospital death in cardiac arrest patient. Champigneulle al and Winther et al reported
that cancer is not associated with higher short or long-term mortality after successful
resuscitation from out of hospital cardiac arrest when adjusting for prognostic factors.
[3]
,[4]
These findings still need further confirmation. Therefore, the aim of present study
was to investigate whether a history of malignant cancer is associated with poor clinical
outcome in post-cardiac arrest patients.- Winther-Jensen M
- Kjaergaard J
- Hassager C
- Køber L
- Lippert F
- Søholm H.
Cancer is not associated with higher short or long-term mortality after successful
resuscitation from out-of-hospital cardiac arrest when adjusting for prognostic factors.
Eur Heart J Acute Cardiovasc Care. 2020; 9 (4_suppl): S184-S192
Keyword
Abbreviations:
cardiac arrest (CA), acute physiology score II (APSII), sequential organ failure assessment (SOFA), International Classification of Diseases (ICD), Medical Information Mart for Intensive Care-IV (The MIMIC-IV), Kaplan–Meier (K-M), Propensity score matching (PSM)To read this article in full you will need to make a payment
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References
- Cancer statistics, 2018.CA Cancer J Clin. 2018; 68: 7-30
- Nallamothu BK. Patterns of resuscitation care and survival after in-hospital cardiac arrest in patients with advanced cancer.J Oncol Pract. 2017; 13: e821-e830
- What is the outcome of cancer patients admitted to the ICU after cardiac arrest? Results from a multicenter study.Resuscitation. 2015; 92: 38-44
- Cancer is not associated with higher short or long-term mortality after successful resuscitation from out-of-hospital cardiac arrest when adjusting for prognostic factors.Eur Heart J Acute Cardiovasc Care. 2020; 9 (4_suppl): S184-S192
- The ethics of resuscitation: how do paramedics experience ethical dilemmas when faced with cancer patients with cardiac arrest?.Prehosp Disaster Med. 2012; 27: 64-70
- In-hospital cardiac arrest: incidence, prognosis and possible measures to improve survival.Intensive Care Med. 2007; 33: 237-245
- Lactate and hypotension as predictors of mortality after in-hospital cardiac arrest.Resuscitation. 2021; 158: 208-214
- MIMIC-IV (version 1.0).PhysioNet. 2021; https://doi.org/10.13026/s6n6-xd98
Article info
Publication history
Published online: February 16, 2022
Accepted:
February 11,
2022
Received in revised form:
February 9,
2022
Received:
January 12,
2022
Identification
Copyright
© 2022 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
