Internal Medicine Flashcards|Articles in Press

Multiple pulmonary opacities. An alarming sign?

Published:March 13, 2023DOI:
      A 60-year-old man with a history of chronic transfusion-dependent β-thalassemia intermedia, splenectomy and secondary hemochromatosis was admitted due to one week of fever and non-respiratory complaints. On physical examination vital signs were normal, short stature and frontal bossing were noted. Blood tests showed leukocytosis of 16,000/µL, hemoglobin of 8.6 g/dL, mcv of 76 fL. Polymerase Chain Reaction (PCR) test for COVID-19 was negative.
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        • Smitaman E.
        • Rubinowitz A.N.
        Images in clinical medicine. extramedullary hematopoiesis associated with beta-thalassemia.
        N Engl J Med. 2010; 362 ([published correction appears in N Engl J Med. 2010 May 27;362(21):2039]): 253
        • Kalchiem-Dekel O.
        • Greenbaum U.
        Extramedullary hematopoiesis in β-thalassemia.
        Mayo Clin Proc. 2015; 90: 1591-1592
        • Roberts A.S.
        • Shetty A.S.
        • Mellnick V.M.
        • Pickhardt P.J.
        • Bhalla S.
        • Menias C.O.
        Extramedullary haematopoiesis: radiological imaging features.
        Clin Radiol. 2016; 71: 807-814