Brief report| Volume 10, ISSUE 1, P49-52, May 1999

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Cardiotoxicity as an adverse effect of 5-fluorouracil


      A patient with a history of coronary artery disease developed chest pain several hours after 5-fluorouracil (5-FU) infusion. Electrocardiograms showed signs of ischemia. Infusion with nitroglycerin provided complete relief from his complaints and normalized the ECG. The literature shows that coronary artery disease increases the risk of ischemic episodes after 5-FU treatment.


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