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Autoimmune serology testing in clinical practice: An updated roadmap for the diagnosis of autoimmune hepatitis
The diagnosis of autoimmune hepatitis (AIH) is based on a combination of clinical, laboratory and histological findings in patients with unexplained acute or chronic hepatitis [1–3]. The disease is considered rare but recent population-based studies from England and New Zealand have shown that AIH incidence is on the rise [4,5]. As in most autoimmune diseases, AIH is characterized by female predominance while every subject can be affected irrespective of age, gender, and ethnicity [6,7]. Differential diagnosis includes viral, toxic, genetic, and metabolic liver diseases [1–3,6].Alcoholic liver disease and autoimmune hepatitis: Sometimes a closer look under the surface is needed
Differential diagnosis of autoimmune hepatitis (AIH) incorporates various liver diseases, including alcoholic liver disease (ALD). We report on clinical, laboratory and outcome characteristics of AIH patients who were initially referred as ALD based on increased alcohol consumption (AIH/ALD).
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