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Malar rash with pancytopenia
A 35-year-old Japanese man presented with a four-month history of persistent flushing and persistent high fever (≥38 °C) for the past several weeks.“Comb and Target signs” in abdominal CT in patients with purpura
A 56-year-old woman complained of nausea, abdominal pain, and bloody diarrhea 10 days prior to the day of consult in our institution. Her abdominal pain worsened and was accompanied by joint pain for several days, prompting a consult at our hospital. Physical examination revealed strong rebound tenderness in the right lower abdomen and the presence of multiple palpable purpuras in the lower extremities (Figure C). Laboratory test results revealed a high C-reactive protein level of 1.21 mg/dL, as well as normal renal function and urinary findings.Chronic urticaria with inflammation
A 67-year-old man presented with a 15-year history of chronic urticaria. It was distributed symmetrically on the limb trunk (Fig. 1A and B) without pruritus. No fever or joint pain or headache is observed. He showed no signs of angioedema. He was referred to our hospital for treatment of chronic urticaria. An antihistamine was ineffective. He was diagnosed with mild sensorineural hearing loss. He had no family history of autoinflammatory diseases.
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